Three Cases of Wegener’s Granulomatosis: ENT Perspectives and Findings
Dr Mohit Vashisth (Consultant ENT Surgeon, JIMS Hisar, Haryana), Dr Ankur Agarwal (Consultant Pathology, Jaipur)
Year: 2024, Volume: 1, Issue: 2, Pages: 108-124, Date of Publication: 31 August 2024
Abstract: This article examines three cases of Wegener’s Granulomatosis, now referred to as Granulomatosis with Polyangiitis (GPA), with a particular emphasis on ENT (ear, nose, and throat) manifestations and clinical observations. GPA is a rare form of Vasculitis that frequently affects the Upper respiratory tract, making early ENT evaluation vital for accurate diagnosis and treatment. The cases presented here illustrate a range of ENT symptoms, such as Chronic sinusitis, Nasal obstruction, and Epistaxis, which played a key role in the initial diagnosis. The detailed clinical assessments and imaging findings shed light on the disease’s progression and the difficulties in distinguishing it from other ENT conditions. This article underscores the essential role of the ENT department in the early detection of systemic diseases, emphasizing the importance of maintaining a high index of suspicion for systemic conditions during ENT evaluations. The case reports highlight the necessity for prompt and comprehensive investigations to ensure accurate diagnosis and timely intervention.
Keywords: Wegener’s Granulomatosis, Granulomatosis with Polyangiitis, ENT, Vasculitis, Chronic Sinusitis, Nasal Obstruction, Epistaxis, Upper Respiratory Tract